SCHEMBL120340

SCHEMBL120340

N[C@@H](Cc1c[nH]c2cc(F)ccc12)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.66
TSHR P16473 3/20 0.66
KDM4E B2RXH2 3/20 0.66
LMNA P02545 3/20 0.66
MAPT P10636 3/20 0.66
BLM P54132 3/20 0.66
PMP22 Q01453 3/20 0.66
MEN1 O00255 3/20 0.66
HIF1A Q16665 2/20 0.66
MPO P05164 2/20 0.66
PTPRA P18433 1/20 0.65
CYP2C19 P33261 1/20 0.62
HTR2A P28223 4/20 0.61
HTR2C P28335 2/20 0.61
ALDH1A1 P00352 2/20 0.61
CYP3A4 P08684 2/20 0.61
ALOX15 P16050 2/20 0.61
NFKB1 P19838 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61
HSD17B10 Q99714 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL248870 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL18029199 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL7096864 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL2330930 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL30381733 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL4262937 0.89 HTR2A (0.60) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL4262934 0.89 HTR2A (0.60) KMT2ATSHRKDM4ELMNAMAPT
Fluorotryptophane SCHEMBL125000 0.89 HTR2A (0.73) KMT2ATSHRKDM4ELMNAMAPT
Fluorotryptophane SCHEMBL29623154 0.89 HTR2A (0.73) KMT2ATSHRKDM4ELMNAMAPT
Fluorotryptophane SCHEMBL29358068 0.89 HTR2A (0.73) KMT2ATSHRKDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1520 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
EP-4659023-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY Immusmol SAS (FR) 2025-12-10 EP claimed
US-20250361273-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC 2025-11-27 US claimed
WO-2025245483-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC (US) 2025-11-27 WO claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
WO-2025128626-A1 HYBRID PEPTIDE COMPOUNDS HAVING A MODIFIED LYSINE RESIDUE CARMOT THERAPEUTICS, INC. (US) 2025-06-19 WO claimed
WO-2025128624-A2 HYBRID PEPTIDE COMPOUNDS HAVING A SUBSTITUTED TRYPTOPHAN RESIDUE OR A TERMINAL SUBSTITUENT CARMOT THERAPEUTICS, INC. (US) 2025-06-19 WO claimed
CN-120082575-A Tryptophan synthase trpB modified gene and preparation method of 6-fluoro-L-tryptophan 宿州学院 2025-06-03 CN claimed
CN-119613495-A C3 complement inhibition polypeptide, preparation method and medical application thereof 远森制药(杭州)有限公司 2025-03-14 CN claimed
CN-112218875-B Method for synthesizing arginine-containing peptides 帝斯曼知识产权资产管理有限公司 2024-10-11 CN claimed
EP-0450327-B1 Biosynthesis of rebeccamycin analogs by tryptophan analogs feeding BRISTOL MYERS SQUIBB CO (US) 1996-06-05 EP claimed
US-5468849-A Rebeccamycin analogs by tryptophan analogs feeding BRISTOL-MYERS SQUIBB COMPANY (US) 1995-11-21 US claimed
EP-0183006-B1 A RECOMBINANT DNA-MOLECULE, CORYNEFORM BACTERIA CARRYING RECOMBINANT DNA AND PROCESS FOR PRODUCING AN AROMATIC AMINO ACID BY USING THE SAME AJINOMOTO CO., INC. (JP) 1992-02-26 EP claimed
EP-0450327-A1 Biosynthesis of rebeccamycin analogs by tryptophan analogs feeding Bristol-Myers Squibb Company (US) 1991-10-09 EP claimed
US-5034318-A Culturing Coryneform glutamic acid producing bacteria with plasmids AJINOMOTO CO., INC. (JP) 1991-07-23 US claimed
US-5017481-A Biosynthesis AJINOMOTO CO., INC. (JP) 1991-05-21 US claimed
US-4704394-A SEROTONIN ANTAGONISTS TECHNOLOGY UNLIMITED, INC. (US) 1987-11-03 US claimed
EP-0183006-A2 A recombinant DNA-molecule, coryneform bacteria carrying recombinant DNA and process for producing an aromatic amino acid by using the same AJINOMOTO CO., INC. (JP) 1986-06-04 EP claimed
US-4371614-A E.Coli bacteria carrying recombinant plasmids and their use in the fermentative production of L-tryptophan AJINOMOTO CO., INC. (JP) 1983-02-01 US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM KMT2A 1848/4885TSHR 1283/4885KDM4E 3819/4885
US-20250361273-A1 METHODS AND COMPOSITIONS MC4R, GPR119, MC2R KMT2A 3419/4885TSHR 120/4885KDM4E 2986/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT KMT2A 2188/4885TSHR 17/4885KDM4E 2649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.