SCHEMBL709704

SCHEMBL709704

O=C(O)c1ccc(-c2nc3cc(C(=O)O)c(C(=O)O)cc3o2)cc1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.51
▸ SNCA P37840 1/20 0.51
▸ MAOA P21397 2/20 0.47
▸ TTR P02766 1/20 0.47
▸ ALB P02768 1/20 0.47
▸ CNR1 P21554 1/20 0.47
▸ DRD1 P21728 1/20 0.47
▸ OPRD1 P41143 1/20 0.47
▸ PDE4D Q08499 1/20 0.47
▸ PDE3A Q14432 1/20 0.47
▸ ESR2 Q92731 10/20 0.46
▸ ESR1 P03372 9/20 0.45
▸ NPC1 O15118 2/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ DHODH Q02127 1/20 0.43
▸ HDAC6 Q9UBN7 4/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29684273 1.00 MAPT (0.51) MAPTSNCAMAOATTRALB
SCHEMBL11136677 0.85 HDAC6 (0.54) MAOATTRALBCNR1DRD1
SCHEMBL9797251 0.77 TTR (0.60) MAPTSNCAMAOATTRALB
SCHEMBL11565318 0.76 SMN1; SMN2 (0.59) MAPTESR2NPC1RAB9AKMT2A
SCHEMBL8579065 0.75 NPC1 (0.55) SNCANPC1RAB9AKMT2AHDAC6
SCHEMBL9797382 0.75 TTR (0.58) MAPTSNCAMAOATTRALB
SCHEMBL824387 0.75 TTR (0.58) MAPTSNCAMAOATTRALB
SCHEMBL11565930 0.74 MAOA (0.57) MAPTMAOATTRALBCNR1
SCHEMBL14030845 0.73 MAPT (0.50) MAPTSNCAMAOATTRALB
SCHEMBL14292186 0.73 GPR119 (0.57) MAPTMAOATTRALBCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150051315-A1 Mixture of Benzoxazine, Epoxy and Anhydride HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2015-02-19 — — US claimed
EP-2814802-A1 MIXTURE OF BENZOXAZINE, EPOXY AND ANHYDRIDE Huntsman Advanced Materials Americas LLC (US) 2014-12-24 — — EP claimed
WO-2013122800-A1 MIXTURE OF BENZOXAZINE, EPOXY AND ANHYDRIDE HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-08-22 — — WO claimed
US-20090242823-A1 PROCESS FOR PREPARING POLYIMIDE BASED COMPOSITIONS USEFUL IN HIGH FREQUENCY CIRCUITRY APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY 2009-10-01 — — US claimed
EP-2001676-A1 CAPACITIVE POLYIMIDE LAMINATE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-17 — — EP claimed
EP-2001942-A1 PROCESS FOR PREPARING POLYIMIDE BASED COMPOSITIONS USEFUL IN HIGH FREQUENCY CIRCUITRY APPLICATIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-17 — — EP claimed
WO-2007126533-A1 CAPACITIVE POLYIMIDE LAMINATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-08 — — WO claimed
WO-2007117372-A1 PROCESS FOR PREPARING POLYIMIDE BASED COMPOSITIONS USEFUL IN HIGH FREQUENCY CIRCUITRY APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-10-18 — — WO claimed
US-20070232734-A1 Polyimide based compositions useful in high frequency circuitry applications and methods relating thereto KANAKARAJAN KARTHIKEYAN 2007-10-04 — — US claimed
US-20070231588-A1 Capacitive polyimide laminate E. I. DU PONT DE NEMOURS AND COMPANY 2007-10-04 — — US claimed
EP-1431984-A1 Polymer resistor composition having a substantially neutral temperature coefficient of resistance and methods and compositions relating thereto E. I. du Pont de Nemours and Company (US) 2004-06-23 — — EP claimed
US-20040113127-A1 Resistor compositions having a substantially neutral temperature coefficient of resistance and methods and compositions relating thereto E.I. DU PONT DE NEMOURS AND COMPANY 2004-06-17 — — US claimed
US-20260109816-A1 ORGANIC REINFORCEMENT OF A POLYAMIDE WITH THE IN SITU SYNTHESIS OF A POLYIMIDE PHASE BY REACTIVE EXTRUSION UNIV CLAUDE BERNARD LYON 1 UCBL (FR) 2026-04-23 — — US disclosed
US-20260109799-A1 ORGANIC REINFORCEMENT OF AN ELASTOMER WITH THE IN SITU SYNTHESIS OF A POLYIMIDE PHASE BY REACTIVE EXTRUSION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2026-04-23 — — US disclosed
US-20260102993-A1 ELECTRICALLY INSULATING LAMINATES FOR ELECTRIC MACHINE APPLICATIONS DUPONT ELECTRONICS INC (US) 2026-04-16 — — US disclosed
US-12564050-B2 Thermal substrates DUPONT ELECTRONICS, INC. 2026-02-24 — — US disclosed
US-5177181-A Semiconductors OCCIDENTAL CHEMICAL CORPORATION (US) 1993-01-05 — — US disclosed
EP-0518060-A2 Polyimidesiloxane extended block copolymers OCCIDENTAL CHEMICAL CORPORATION (US) 1992-12-16 — — EP disclosed
EP-0517002-A2 Diamines and photosensitive polyimides made therefrom OCCIDENTAL CHEMICAL CORPORATION (US) 1992-12-09 — — EP disclosed
US-4369302-A Curable resin composition comprising cyanate ester and polyisocyanate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-01-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109799-A1 ORGANIC REINFORCEMENT OF AN ELASTOMER WITH THE IN SITU SYNTHESIS OF A POLYIMIDE PHASE BY REACTIVE EXTRUSION EED, ELL, EIF2B4 MAPT 3228/4885SNCA 3724/4885MAOA 4427/4885
US-20260102993-A1 ELECTRICALLY INSULATING LAMINATES FOR ELECTRIC MACHINE APPLICATIONS AS3MT, SMCHD1, ASH2L MAPT 246/4885SNCA 4360/4885MAOA 2634/4885
US-20260109816-A1 ORGANIC REINFORCEMENT OF A POLYAMIDE WITH THE IN SITU SYNTHESIS OF A POLYIMIDE PHASE BY REACTIVE EXTRUSION PUF60, RICTOR, INF2 MAPT 1314/4885SNCA 2613/4885MAOA 1081/4885
US-12564050-B2 Thermal substrates TTN, AS3MT, SCO2 MAPT 207/4885SNCA 340/4885MAOA 366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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