Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910551 | 0.82 | PTGES (0.42) | — | |
| SCHEMBL7100804 | 0.81 | HPGD (0.40) | MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL5275334 | 0.78 | CSNK1E (0.49) | — | |
| SCHEMBL5268869 | 0.77 | CSNK1E (0.47) | — | |
| SCHEMBL11028392 | 0.76 | MME (0.40) | MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL18241280 | 0.75 | BMP1 (0.53) | SIRT2SIRT1 | |
| SCHEMBL18241278 | 0.75 | BMP1 (0.53) | SIRT2SIRT1 | |
| SCHEMBL16898201 | 0.75 | TLL1 (0.41) | — | |
| SCHEMBL20587176 | 0.75 | TLL1 (0.41) | — | |
| SCHEMBL16898198 | 0.75 | TLL1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |