Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.59 |
| ▸ | CSF1R | P07333 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101436 | 0.82 | CYSLTR2 (0.56) | NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29932805 | 0.81 | MAOB (0.50) | — | |
| SCHEMBL7098576 | 0.81 | MAOB (0.50) | — | |
| SCHEMBL7104449 | 0.78 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DPKM | |
| SCHEMBL8413386 | 0.76 | CYSLTR2 (0.49) | RAB9ASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL743919 | 0.73 | CSF1R (0.66) | CSF1R | |
| SCHEMBL23364824 | 0.72 | KCNH2 (0.45) | APPPKMMEN1KMT2AKDM4E | |
| SCHEMBL23364576 | 0.72 | CYSLTR2 (0.53) | PKMSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL7104596 | 0.72 | CYSLTR2 (0.49) | RAB9A | |
| SCHEMBL10731769 | 0.71 | MTNR1A (0.64) | APPNPC1RAB9APKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |