Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098998 | 0.87 | RORC (0.44) | GAAMRGPRX4MEN1KMT2AALDH1A1 | |
| SCHEMBL17731234 | 0.82 | MRGPRX4 (0.48) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL7097124 | 0.78 | APP (0.59) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL25309520 | 0.78 | QDPR (0.45) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL7098406 | 0.76 | SLC9A1 (0.42) | POLBTP53 | |
| SCHEMBL20852873 | 0.75 | IDO1 (0.63) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL20838654 | 0.75 | IDO1 (0.63) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17737044 | 0.75 | IDO1 (0.63) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17737411 | 0.75 | IDO1 (0.63) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7103500 | 0.74 | ESR2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |