Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850877 | 0.81 | KDM4E (0.50) | POLBKDM4EALDH1A1RAB9AKMT2A | |
| SCHEMBL6850920 | 0.79 | NPC1 (0.41) | KDM4EALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL6846948 | 0.77 | KDM4E (0.40) | POLBKDM4EALDH1A1KMT2A | |
| SCHEMBL6846803 | 0.76 | CCR2 (0.41) | POLBALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL6849677 | 0.76 | L3MBTL1 (0.43) | POLBKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL6846909 | 0.76 | LMNA (0.45) | POLBLMNA | |
| Hydrochloric Acid SCHEMBL6851033 | 0.75 | L3MBTL1 (0.42) | POLBKDM4EALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7096357 | 0.75 | LMNA (0.44) | POLBLMNA | |
| SCHEMBL6847031 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KMT2ALMNAHTT | |
| SCHEMBL6849763 | 0.74 | KDM4E (0.49) | KDM4EALDH1A1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268484-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068652-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |