SCHEMBL7097154

SCHEMBL7097154

CC(C)(C)CCN[C@@H](CC(=O)O)C(=O)OC(=O)[C@H](CC(=O)O)NCCC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RRM1 P23921 1/20 0.32
RRM2 P31350 1/20 0.32
RRM2B Q7LG56 1/20 0.32
SIGMAR1 Q99720 1/20 0.31
CCKBR P32239 1/20 0.31
GRN P28799 1/20 0.31
SORT1 Q99523 1/20 0.31
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
PGD P52209 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13887635 0.90 ITGB3 (0.33) RRM1RRM2RRM2BSIGMAR1CCKBR
SCHEMBL29241835 0.90 ITGB3 (0.33) RRM1RRM2RRM2BSIGMAR1CCKBR
SCHEMBL7097602 0.85
SCHEMBL5335559 0.84 GRN (0.39) RRM1RRM2RRM2BSIGMAR1CCKBR
SCHEMBL7099887 0.84 GRN (0.39) RRM1RRM2RRM2BSIGMAR1CCKBR
Hydrochloric Acid SCHEMBL7101089 0.82 GRN (0.38) RRM1RRM2RRM2BSIGMAR1CCKBR
SCHEMBL7213444 0.81 CCKBR (0.34) RRM1RRM2RRM2BSIGMAR1CCKBR
SCHEMBL7097493 0.79 CA1 (0.33)
SCHEMBL10253834 0.78 CYP2D6 (0.39) POLBTDP1
SCHEMBL7213859 0.76 GRN (0.36) GRNSORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140795-B1 N-3, 3-DIMETHYLBUTYL-L-ASPARTIC ACID AND ESTERS THEREOF, THE PROCESS OF PREPARING THE SAME, AND THE PROCESS FOR PREPARING N-[N-(3,3-DIMETHYLBUTYL)-L-ALPHA-ASPARTYL)-L-PHENYLALANINE-1-METHYLESTER THEREFROM NUTRASWEET CO (US) 2003-09-03 EP claimed
US-6077962-A N-3, 3-dimethylbutyl-L-aspartic acid and esters thereof, the process of preparing the same, and the process for preparing N-(N-(3,3-dimethylbutyl) -α L-aspartyl)-L- phenylalanine 1-methyl ester therefrom THE NUTRASWEET COMPANY (US) 2000-06-20 US claimed