Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.34 |
| ▸ | GRN | P28799 | 2/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | RRM2 | P31350 | 1/20 | 0.32 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099887 | 0.85 | GRN (0.39) | CCKBRGRNSORT1RRM1RRM2 | |
| SCHEMBL5335559 | 0.85 | GRN (0.39) | CCKBRGRNSORT1RRM1RRM2 | |
| Hydrochloric Acid SCHEMBL7101089 | 0.84 | GRN (0.38) | CCKBRGRNSORT1RRM1RRM2 | |
| SCHEMBL13887635 | 0.81 | ITGB3 (0.33) | CCKBRGRNSORT1RRM1RRM2 | |
| SCHEMBL7097154 | 0.81 | RRM1 (0.32) | CCKBRGRNSORT1RRM1RRM2 | |
| SCHEMBL29241835 | 0.81 | ITGB3 (0.33) | CCKBRGRNSORT1RRM1RRM2 | |
| SCHEMBL8323771 | 0.73 | RRM1 (0.37) | CCKBRRRM1RRM2RRM2B | |
| SCHEMBL29017706 | 0.71 | CASP1 (0.35) | — | |
| SCHEMBL29017705 | 0.71 | CASP1 (0.35) | — | |
| SCHEMBL13887636 | 0.71 | MLYCD (0.34) | RRM1RRM2RRM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627431-B1 | Hydrolyzing the ester using a lipase from Pseudomonas and esterase from porcine liver; use as artificial sweetener | THE NUTRASWEET COMPANY | 2003-09-30 | — | — | US | disclosed |
| WO-2001085977-A2 | CHEMOENZYMATIC SYNTHESIS OF NEOTAME | THE NUTRASWEET COMPANY (US) | 2001-11-15 | — | — | WO | disclosed |