Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21014821 | 0.70 | KMT2A (0.55) | ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL7097192 | 0.70 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL9576406 | 0.69 | LMNA (0.62) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL9723828 | 0.68 | GAA (0.38) | L3MBTL1KMT2AMEN1TDP1GAA | |
| SCHEMBL2364796 | 0.68 | GNAI3 (0.58) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL9576495 | 0.67 | LMNA (0.65) | MAPTLMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL7029657 | 0.67 | BRD4 (0.39) | ALDH1A1MAPTL3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL9066382 | 0.66 | GAA (0.45) | ALDH1A1KMT2AMEN1GAAGNAI3 | |
| SCHEMBL8162071 | 0.66 | GAA (0.44) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL16405435 | 0.66 | GNAI3 (0.60) | ALDH1A1MAPTLMNAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |