Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.47 |
| ▸ | MLNR | O43193 | 2/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376781 | 0.84 | HTR7 (0.56) | LMNASIGMAR1CXCR4MLNRHTR7 | |
| SCHEMBL7098972 | 0.83 | HTR7 (0.59) | LMNASIGMAR1CXCR4MLNRPDCD1 | |
| SCHEMBL1111705 | 0.83 | HTR7 (0.43) | SIGMAR1OPRM1OPRK1HTR7 | |
| Hydrochloric Acid SCHEMBL30688262 | 0.83 | HTR7 (0.55) | LMNASIGMAR1CXCR4MLNRHTR7 | |
| Hydrochloric Acid SCHEMBL5689236 | 0.83 | HTR7 (0.55) | LMNASIGMAR1CXCR4MLNRHTR7 | |
| SCHEMBL11370179 | 0.81 | CXCR4 (0.48) | SIGMAR1CXCR4HTR7 | |
| SCHEMBL7102078 | 0.81 | LMNA (0.55) | LMNASIGMAR1CXCR4OPRM1OPRD1 | |
| SCHEMBL2472212 | 0.81 | HTR7 (0.64) | LMNASIGMAR1CXCR4MLNRHTR7 | |
| SCHEMBL30616744 | 0.81 | HTR7 (0.64) | LMNASIGMAR1CXCR4MLNRHTR7 | |
| SCHEMBL4650265 | 0.80 | SIGMAR1 (0.48) | LMNASIGMAR1CXCR4MLNRPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |