Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.48 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | VEGFA | P15692 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11969503 | 0.95 | OPRD1 (0.52) | SPHK2SPHK1FAAHOPRD1 | |
| SCHEMBL11990419 | 0.90 | GBA1 (0.44) | OPRD1 | |
| SCHEMBL14822485 | 0.81 | OPRD1 (0.53) | SPHK2SPHK1OPRD1 | |
| SCHEMBL3689270 | 0.81 | OPRD1 (0.53) | SPHK2SPHK1OPRD1 | |
| SCHEMBL11459718 | 0.81 | CCR2 (0.49) | SPHK2SPHK1 | |
| SCHEMBL11969233 | 0.81 | OPRD1 (0.50) | OPRD1VEGFAEGLN1 | |
| SCHEMBL2997593 | 0.80 | — | — | |
| SCHEMBL1902756 | 0.80 | FAAH (0.53) | SPHK2SPHK1FAAHOPRD1 | |
| SCHEMBL5530480 | 0.80 | — | — | |
| SCHEMBL7315616 | 0.80 | FAAH (0.53) | SPHK2SPHK1FAAHOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140952-B1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | BIOAGENCY AG (DE) | 2003-09-03 | — | — | EP | disclosed |
| EP-1140952-A1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | Jomaa Pharmaka GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037477-A1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | JOMAA PHARMAKA GMBH (DE) | 2000-06-29 | — | — | WO | disclosed |
| EP-0381959-A1 | Cyclohexaneacetamide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-16 | — | — | EP | disclosed |