⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086663 | 0.71 | RAB9A (0.43) | — | |
| SCHEMBL7100097 | 0.71 | CHRM1 (0.30) | — | |
| SCHEMBL1673128 | 0.69 | — | — | |
| SCHEMBL5796400 | 0.69 | GRM5 (0.36) | — | |
| SCHEMBL2458453 | 0.66 | CCR1 (0.41) | — | |
| SCHEMBL1421802 | 0.66 | NOS1 (0.35) | — | |
| SCHEMBL5252596 | 0.66 | — | — | |
| SCHEMBL9996915 | 0.66 | GAA (0.41) | — | |
| SCHEMBL271615 | 0.66 | — | — | |
| SCHEMBL1673907 | 0.66 | SIRT2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370559-A1 | TRIAZOLOPYRIDINES AS ANTI-INFLAMMATORY AGENTS | Pfizer Products Inc. (US) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002072579-A1 | TRIAZOLOPYRIDINES AS ANTI-INFLAMMATORY AGENTS | PFIZER PRODUCTS INC. (US) | 2002-09-19 | — | — | WO | disclosed |