SCHEMBL7098341

SCHEMBL7098341

Cc1c(O)c(O)c(Cl)c(Cl)c1C(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11523389 0.81 MEN1 (0.35) MEN1ALDH1A1LMNAMAPTHPGD
SCHEMBL11523925 0.81
SCHEMBL7044766 0.74
SCHEMBL24599548 0.71 GABRA1 (0.33)
SCHEMBL5587049 0.71 HPGD (0.44) MEN1ALDH1A1LMNAMAPTHPGD
SCHEMBL11060919 0.71 HPGD (0.37) MEN1ALDH1A1LMNAMAPTHPGD
SCHEMBL5590229 0.71 TSHR (0.53) MEN1ALDH1A1LMNAMAPTHPGD
SCHEMBL1476599 0.71
SCHEMBL11720809 0.69
SCHEMBL10922334 0.68 HPGD (0.47) MEN1ALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102959019-B Method for forming multilayer coating film KANSAI PAINT CO LTD 2015-05-13 CN disclosed
CN-102959019-A Method for forming multilayer coating film KANSAI PAINT CO LTD 2013-03-06 CN disclosed
US-6610813-B2 Low number of hydrogen-carbon bonds; for example polyester derived from 2,3,5,6-tetrachloro-p-xylylene glycol and chlorendic acid; use as waveguide core and/or cladding material in optical fibers and optical devices CORNING INCORPORATED 2003-08-26 US disclosed
US-20030013833-A1 Highly-halogenated low optical loss polymer HORN KEITH A (US) 2003-01-16 US disclosed
US-6470131-B1 A POLYESTER, POLYLACTONE OR POLYCARBONATE HAVING LESS THAN 50 HYDROGEN-CARBON BONDS PER 1000 MOLECULAR WEIGHT UNITS USED AS WAVEGUIDE CORE MATERIAL AND/OR A WAVEGUIDE CLADDING MATERIAL IN OPTICAL FIBERS AND/OR PLANAR OPTICAL DEVICES. CORNING INCORPORATED 2002-10-22 US disclosed
WO-2002036659-A2 HIGHLY-HALOGENATED LOW OPTICAL LOSS POLYESTER CORNING INCORPORATED (US) 2002-05-10 WO disclosed
US-4075238-A Polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1978-02-21 US disclosed