Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100679 | 0.91 | POLB (0.55) | POLBMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7100629 | 0.76 | SLC6A2 (0.46) | POLBMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL27807116 | 0.76 | SLC6A3 (0.47) | POLBMEN1KMT2AMAPTSLC6A3 | |
| SCHEMBL11756772 | 0.75 | PKM (0.47) | MEN1KMT2APTGS1MAPTHTT | |
| Water SCHEMBL11756765 | 0.74 | PKM (0.46) | MEN1KMT2APTGS1MAPTHTT | |
| SCHEMBL7103544 | 0.73 | SLC6A2 (0.62) | MEN1KMT2AMAPTHTTSLC6A3 | |
| SCHEMBL4868386 | 0.72 | HTR2C (0.49) | POLBMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL9809565 | 0.72 | CHRM3 (0.61) | MEN1KMT2AMAPTHTTSLC6A3 | |
| SCHEMBL1566474 | 0.71 | ALOX5 (0.51) | ALDH1A1SLC6A3 | |
| SCHEMBL28787293 | 0.71 | BCHE (0.45) | SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |