Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098532 | 0.91 | POLB (0.47) | POLBALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL27807116 | 0.81 | SLC6A3 (0.47) | POLBMEN1KMT2ACYP3A4SLC6A3 | |
| SCHEMBL4868386 | 0.80 | HTR2C (0.49) | POLBALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL7103544 | 0.78 | SLC6A2 (0.62) | MEN1KMT2ACYP1A2CYP3A4SLC6A3 | |
| SCHEMBL9809565 | 0.77 | CHRM3 (0.61) | MEN1KMT2ACYP1A2CYP3A4SLC6A3 | |
| SCHEMBL28787293 | 0.76 | BCHE (0.45) | CYP1A2CYP3A4SLC6A3TSHR | |
| SCHEMBL6984545 | 0.75 | MEN1 (0.50) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL24765275 | 0.75 | L3MBTL1 (0.55) | POLBALDH1A1NPC1RAB9AMTNR1A | |
| SCHEMBL12193236 | 0.74 | FFAR1 (0.65) | — | |
| SCHEMBL12193237 | 0.74 | FFAR1 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |