Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28186866 | 0.88 | ALOX5 (0.39) | ALDH1A1HSD17B10LMNAKMT2AALOX5 | |
| SCHEMBL11209111 | 0.86 | ALOX5 (0.41) | ALDH1A1HSD17B10GAAALOX5 | |
| SCHEMBL1306308 | 0.82 | BRD4 (0.40) | ALDH1A1HSD17B10LMNAGAAUSP2 | |
| SCHEMBL8915607 | 0.80 | GNAI3 (0.41) | ALDH1A1POLBGAAALOX5 | |
| SCHEMBL7097192 | 0.76 | ALDH1A1 (0.39) | ALDH1A1LMNAHPGDL3MBTL1GAA | |
| SCHEMBL7368280 | 0.75 | TSHR (0.34) | LMNAKMT2A | |
| SCHEMBL9264820 | 0.74 | — | — | |
| SCHEMBL28241875 | 0.73 | ALOX5 (0.34) | ALDH1A1L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL7098663 | 0.72 | ADH1B (0.33) | — | |
| SCHEMBL11816203 | 0.71 | HTT (0.44) | ALDH1A1HSD17B10LMNAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |