Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22090241 | 0.82 | AURKA (0.44) | AURKARPS6KB1EPHX2ALDH1A1NPC1 | |
| SCHEMBL7097815 | 0.74 | MAPT (0.41) | ALDH1A1LMNARECQLKDM4EKMT2A | |
| SCHEMBL9510379 | 0.74 | KMT2A (0.52) | ALDH1A1NPC1LMNAKDM4EKMT2A | |
| SCHEMBL1234127 | 0.73 | AURKA (0.52) | AURKARPS6KB1ALDH1A1NPC1KDM4E | |
| SCHEMBL167398 | 0.71 | SIGMAR1 (0.52) | ALDH1A1LMNAKDM4EKMT2AMAPK1 | |
| SCHEMBL6263848 | 0.71 | ALOX5 (0.37) | ALDH1A1LMNASOAT1KMT2APOLB | |
| SCHEMBL7973627 | 0.70 | ALDH1A1 (0.48) | ALDH1A1LMNASOAT1KMT2APOLB | |
| SCHEMBL8801214 | 0.69 | MAP4K4 (0.49) | NPC1LMNAKDM4EPOLBL3MBTL1 | |
| SCHEMBL2360638 | 0.67 | AURKA (0.60) | AURKARPS6KB1ALDH1A1LMNAKDM4E | |
| SCHEMBL6078641 | 0.67 | AURKA (0.56) | AURKARPS6KB1EPHX2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091940-B1 | METHOD FOR PREPARING 1-ALKYL-PYRAZOL-5-CARBOXYLIC ACID ESTERS | BAYER AG (DE) | 2003-09-10 | — | — | EP | disclosed |
| EP-0854142-B1 | Process for the preparation of 1-alkylpyrazole-5-carboxylic esters | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| EP-1091940-A1 | METHOD FOR PREPARING 1-ALKYL-PYRAZOL-5-CARBOXYLIC ACID ESTERS | Bayer Aktiengesellschaft (DE) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001673-A2 | METHOD FOR PREPARING 1-ALKYL-PYRAZOL-5-CARBOXYLIC ACID ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-13 | — | — | WO | disclosed |
| EP-0854142-A1 | Process for the preparation of 1-alkylpyrazole-5-carboxylic esters | BAYER AG (DE) | 1998-07-22 | — | — | EP | disclosed |