Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866240 | 0.98 | ALOX15 (0.53) | ALOX15HRH3KCNH2HRH4TBXAS1 | |
| SCHEMBL7455224 | 0.90 | ALOX15 (0.55) | ALOX15HRH3KCNH2HRH4TBXAS1 | |
| Hydrochloric Acid SCHEMBL28306930 | 0.88 | ALOX15 (0.53) | ALOX15HRH3KCNH2HRH4TBXAS1 | |
| SCHEMBL9867321 | 0.84 | ALOX15 (0.49) | ALOX15HRH3KCNH2TBXAS1PARP1 | |
| Bicarbonate SCHEMBL28339489 | 0.83 | TBXAS1 (0.48) | ALOX15HRH3KCNH2TBXAS1CYP1A2 | |
| Formic Acid SCHEMBL28874959 | 0.81 | ALOX15 (0.46) | ALOX15HRH3KCNH2HRH4TBXAS1 | |
| SCHEMBL27279466 | 0.81 | ALOX15 (0.49) | ALOX15HRH3KCNH2HRH4TBXAS1 | |
| SCHEMBL17887905 | 0.79 | SIGMAR1 (0.45) | ALOX15HRH3KCNH2HRH4HRH1 | |
| SCHEMBL18325377 | 0.79 | ALOX15 (0.81) | ALOX15HRH3KCNH2HRH4PARP1 | |
| SCHEMBL807358 | 0.79 | ALOX15 (0.81) | ALOX15HRH3KCNH2HRH4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051144-B1 | USE OF HETEROCYCLIC QUATERNARY POLYAMMONIUM POLYMERS AS PROTECTIVE AGENT FOR KERATIN FIBRES AND COSMETIC COMPOSITIONS | OREAL (FR) | 2003-09-03 | — | — | EP | disclosed |
| US-6416770-B1 | Use of heterocyclic quaternary polyammonium polymers as protective agent for keratin fibres and cosmetic compositions | L'ORéAL S.A. (FR) | 2002-07-09 | — | — | US | disclosed |
| EP-1051144-A1 | USE OF HETEROCYCLIC QUATERNARY POLYAMMONIUM POLYMERS AS PROTECTIVE AGENT FOR KERATIN FIBRES AND COSMETIC COMPOSITIONS | L'OREAL (FR) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037276-A1 | USE OF HETEROCYCLIC QUATERNARY POLYAMMONIUM POLYMERS AS PROTECTIVE AGENT FOR KERATIN FIBRES AND COSMETIC COMPOSITIONS | L'OREAL (FR) | 1999-07-29 | — | — | WO | disclosed |
| EP-0861245-A1 | PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES | MERCK SHARP & DOHME LTD. (GB) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997019073-A1 | PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |
| US-5011838-A | Antiallergens, antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-04-30 | — | — | US | disclosed |
| EP-0397615-A2 | Pharmacologically active 2-substituted 3-(2-ethoxyethyl) imidazo [4,5-b] pyridines and pharmaceutical compositions containing them | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-11-14 | — | — | EP | disclosed |