Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145906 | 0.90 | ALOX15 (0.51) | ALOX15SIGMAR1POLBHTR1DHTR1B | |
| SCHEMBL9866240 | 0.85 | ALOX15 (0.53) | ALOX15HTR1DHTR1BTBXAS1KCNH2 | |
| SCHEMBL7100019 | 0.84 | ALOX15 (0.51) | ALOX15HTR1DHTR1BTBXAS1CYP1A2 | |
| SCHEMBL7278898 | 0.80 | ALOX15 (0.76) | ALOX15HTR1DHTR1BHTTKMT2A | |
| SCHEMBL27279466 | 0.78 | ALOX15 (0.49) | ALOX15SIGMAR1HTR1DHTR1BTBXAS1 | |
| SCHEMBL8776471 | 0.77 | HTR1A (0.56) | ALOX15HTR2AHRH3 | |
| SCHEMBL18325474 | 0.75 | ALOX15 (0.67) | ALOX15HTR1DHTR1BKMT2AALDH1A1 | |
| SCHEMBL7455224 | 0.73 | ALOX15 (0.55) | ALOX15SIGMAR1TBXAS1CYP1A2KCNH2 | |
| SCHEMBL3431746 | 0.73 | TBXAS1 (0.66) | ALOX15TBXAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9777191 | 0.73 | TBXAS1 (0.60) | ALOX15TBXAS1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011838-A | Antiallergens, antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-04-30 | — | — | US | disclosed |
| EP-0397615-A2 | Pharmacologically active 2-substituted 3-(2-ethoxyethyl) imidazo [4,5-b] pyridines and pharmaceutical compositions containing them | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-11-14 | — | — | EP | disclosed |