Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2388976 | 0.79 | CNR2 (0.46) | LOXL2GPR3TAS1R3TAS1R1MEN1 | |
| SCHEMBL586085 | 0.77 | GPR3 (0.44) | LOXL2GPR3TAS1R3TAS1R1MEN1 | |
| SCHEMBL2702753 | 0.77 | LOXL2 (0.63) | LOXL2GPR3TAS1R3TAS1R1MEN1 | |
| SCHEMBL1035524 | 0.77 | LOXL2 (0.48) | LOXL2GPR3TAS1R3TAS1R1MEN1 | |
| SCHEMBL719251 | 0.77 | GPR3 (0.44) | LOXL2GPR3TAS1R3TAS1R1MEN1 | |
| SCHEMBL6323143 | 0.76 | TAS1R3 (0.49) | LOXL2GPR3TAS1R3TAS1R1MEN1 | |
| SCHEMBL2387916 | 0.76 | CNR2 (0.49) | LOXL2GPR3TAS1R3TAS1R1MEN1 | |
| SCHEMBL13328626 | 0.74 | CNR1 (0.50) | LOXL2GPR3TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL4775813 | 0.74 | LOXL2 (0.42) | LOXL2GPR3TAS1R3TAS1R1MEN1 | |
| SCHEMBL1253465 | 0.74 | TAS1R3 (0.47) | LOXL2GPR3TAS1R3TAS1R1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226138-A4 | FAB I INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-1226138-A1 | FAB I INHIBITORS | SmithKline Beecham Corporation (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001027103-A1 | FAB I INHIBITORS | SMITHKLINE BEECHAM CORPORATION (GB) | 2001-04-19 | — | — | WO | disclosed |