Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6118386 | 0.84 | ALDH1A1 (0.41) | LOXL2GPR3TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL7984828 | 0.80 | TAS1R3 (0.41) | LOXL2GPR3TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL2388976 | 0.79 | CNR2 (0.46) | LOXL2GPR3TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL1035524 | 0.77 | LOXL2 (0.48) | LOXL2GPR3TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL2702753 | 0.77 | LOXL2 (0.63) | LOXL2GPR3TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL719251 | 0.77 | GPR3 (0.44) | LOXL2GPR3TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL586085 | 0.77 | GPR3 (0.44) | LOXL2GPR3TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL2387916 | 0.76 | CNR2 (0.49) | LOXL2GPR3TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL13328626 | 0.74 | CNR1 (0.50) | LOXL2GPR3TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL7100115 | 0.74 | LOXL2 (0.42) | LOXL2GPR3TAS1R3TAS1R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973902-A2 | 3-HETEROCYCLYLACRYLAMIDE COMPOUNDS AS FABI INHIBITORS AND ANTIBACTERIAL AGENTS | Affinium Pharmaceuticals, Inc. (CA) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007067416-A2 | HETEROCYCLYLACRYLAMIDE COMPOUNDS AS FABI INHIBITORS AND ANTIBACTERIAL AGENTS | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2007-06-14 | — | — | WO | disclosed |