Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099299 | 0.89 | DRD3 (0.50) | ADRA1ADRD2DRD4HTR2AHTR7 | |
| SCHEMBL7097660 | 0.85 | DRD3 (0.57) | ADRA1ADRD2DRD4HTR2AHTR7 | |
| SCHEMBL7099285 | 0.85 | DRD3 (0.57) | ADRA1ADRD2DRD4HTR2AHTR7 | |
| SCHEMBL7103672 | 0.85 | DRD3 (0.57) | ADRA1ADRD2DRD4HTR2AHTR7 | |
| SCHEMBL7097625 | 0.85 | DRD3 (0.57) | ADRA1ADRD2DRD4HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL7101884 | 0.84 | DRD3 (0.56) | ADRA1ADRD2DRD4HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL7097383 | 0.84 | DRD3 (0.56) | ADRA1ADRD2DRD4HTR2AHTR7 | |
| SCHEMBL7098292 | 0.84 | DRD2 (0.42) | ACHEADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL7101925 | 0.81 | ACHE (0.50) | ACHEADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL7101905 | 0.81 | ACHE (0.50) | ACHEADRA1AADRA1BDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |