Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.42 |
| ▸ | DRD3 | P35462 | 6/20 | 0.42 |
| ▸ | HTR7 | P34969 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103905 | 0.88 | DRD2 (0.45) | DRD2DRD3HTR2AIDH1 | |
| SCHEMBL7098294 | 0.87 | DRD2 (0.42) | DRD2DRD3DRD4ADRA1B | |
| SCHEMBL7100671 | 0.84 | ACHE (0.51) | DRD2DRD3HTR7HTR2ADRD4 | |
| SCHEMBL7773713 | 0.82 | DRD2 (0.52) | DRD2DRD3HTR7HTR2ADRD4 | |
| Hydrochloric Acid SCHEMBL7775564 | 0.82 | IDH1 (0.45) | DRD2DRD3HTR7HTR2ADRD4 | |
| SCHEMBL7775646 | 0.81 | OPRD1 (0.46) | DRD2DRD3HTR7HTR2ADRD4 | |
| SCHEMBL7103907 | 0.78 | DRD2 (0.42) | DRD2DRD3 | |
| SCHEMBL7099285 | 0.75 | DRD3 (0.57) | DRD2DRD3HTR7HTR2ADRD4 | |
| SCHEMBL7097660 | 0.75 | DRD3 (0.57) | DRD2DRD3HTR7HTR2ADRD4 | |
| SCHEMBL7103672 | 0.75 | DRD3 (0.57) | DRD2DRD3HTR7HTR2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |