Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697402 | 0.87 | ALDH1A1 (0.43) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL540821 | 0.82 | KDM4E (0.39) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL12964261 | 0.81 | NOS3 (0.42) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL18951028 | 0.79 | HSPA5 (0.37) | MEN1KMT2AALDH1A1CASP7CYP1A2 | |
| SCHEMBL18421759 | 0.79 | KDM4E (0.45) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL421525 | 0.79 | SKP2 (0.43) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7032888 | 0.78 | HTT (0.43) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL19785965 | 0.77 | CYP3A4 (0.40) | TDP1ALDH1A1CASP7CYP1A2ALOX15 | |
| SCHEMBL20614207 | 0.77 | ALDH1A1 (0.35) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL11030450 | 0.77 | GPR84 (0.45) | KDM4EMEN1KMT2ATDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551250-A | Preparation method of diethyl toluenediamine | 河南雷佰瑞新材料科技有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-117551250-A | Preparation method of diethyl toluenediamine | 河南雷佰瑞新材料科技有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117551250-A | Preparation method of diethyl toluenediamine | 河南雷佰瑞新材料科技有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-112755570-A | Diethyl toluene diamine hydrolysis solvent distillation recovery unit | 张淑侠 | 2021-05-07 | — | — | CN | disclosed |
| CN-112403009-B | Diethyl toluene diamine hydrolysis solvent distillation recovery unit | 东营海瑞宝新材料有限公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-112403009-A | Diethyl toluene diamine hydrolysis solvent distillation recovery unit | 东营海瑞宝新材料有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-211798866-U | Diethyl toluene diamine hydrolysis solvent distillation recovery unit | 河南雷佰瑞新材料科技有限公司 | 2020-10-30 | — | — | CN | disclosed |
| EP-1147141-B1 | ENERGY MANAGEMENT POLYURETHANE RIGID FOAMS WITH HIGH RECOVERY | BAYER ANTWERPEN NV (BE) | 2003-02-12 | — | — | EP | disclosed |
| US-6127443-A | HIGH ENERGY ABSORBING EFFICIENCY AS WELL AS EXCEPTIONAL RECOVERY AFTER DEFORMATION, ALLOWING THEIR USE IN VISIBLE ENERGY ABSORBING STRUCTURES, PARTICULARLY IN THE TRANSPORTATION VEHICLE INDUSTRY | BAYER ANTWERP N.V. (BE) | 2000-10-03 | — | — | US | disclosed |
| EP-0683803-A1 | ADHESION PROMOTERS. | AKZO NOBEL NV (NL) | 1995-11-29 | — | — | EP | disclosed |
| EP-0228190-B1 | RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION | ETHYL CORPORATION (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0351814-A2 | Poly (N-cyclic iminoether), processes for production thereof, thermosetting composition containing it and thermoset resin | TEIJIN LIMITED (JP) | 1990-01-24 | — | — | EP | disclosed |
| US-4868225-A | STERICALLY HINDERED META-PHENYLENEDIAMINE CHAIN EXTENDER FOR POLYURETHANES | THE DOW CHEMICAL COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| US-4866208-A | CURING AGENT FOR EPOXY RESINS; EXTENDERS FOR POLYUREA-URETHANE COPOLYMERS | THE DOW CHEMICAL COMPANY (US) | 1989-09-12 | — | — | US | disclosed |
| US-4861914-A | 2,6-DI-TERT-BUTYL-P-CRESOL | ETHYL CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
| US-4792623-A | CURING AGENT, EXTENDER | THE DOW CHEMICAL COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0228190-A2 | RIM polyurethanes comprising mixed diamine chain extenders and process and composition for their production | ETHYL CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4631298-A | REACTION INJECTION MOLDING POLYURETHANES | ETHYL CORPORATION (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0082258-B1 | SUBSTITUTED M-PHENYLENEDIAMINES | THE DOW CHEMICAL COMPANY (US) | 1986-02-19 | — | — | EP | disclosed |
| EP-0082258-A1 | Substituted m-phenylenediamines | THE DOW CHEMICAL COMPANY (US) | 1983-06-29 | — | — | EP | disclosed |