Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | NQO2 | P16083 | 6/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5338799 | 0.83 | NQO2 (0.67) | MAOBNQO2MTNR1AMEN1KMT2A | |
| SCHEMBL7099888 | 0.81 | MTNR1A (0.72) | NQO2MTNR1AMTNR1B | |
| SCHEMBL7026214 | 0.81 | TP53 (0.54) | NQO2TRPV1MTNR1AMEN1KMT2A | |
| SCHEMBL7020477 | 0.80 | MTNR1A (0.53) | NQO2MTNR1AMEN1KMT2AMTNR1B | |
| SCHEMBL5343419 | 0.80 | MTNR1A (0.70) | NQO2MTNR1AMTNR1BMAPT | |
| SCHEMBL7099796 | 0.79 | MTNR1A (0.51) | NQO2MTNR1AMTNR1B | |
| SCHEMBL7019162 | 0.78 | MTNR1A (0.67) | NQO2MTNR1AMTNR1B | |
| SCHEMBL5341459 | 0.76 | NQO2 (0.74) | NQO2MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL5341366 | 0.76 | MTNR1A (0.71) | NQO2MTNR1AMTNR1B | |
| SCHEMBL8690168 | 0.74 | HTR1A (0.48) | MAOBNQO2MTNR1AKMT2AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |