Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690172 | 0.88 | PIM1 (0.58) | ALDH1A1TSHRNPSR1PIM1KDM4E | |
| SCHEMBL8017016 | 0.86 | HTR1A (0.54) | HTR1AHTR1DHTR2CSIRT1ALDH1A1 | |
| SCHEMBL24938760 | 0.84 | ALOX15 (0.59) | SIRT1ALDH1A1TSHRNPSR1PIM1 | |
| SCHEMBL2656059 | 0.83 | ALDH1A1 (0.47) | HTR1AHTR1DHTR2CALDH1A1MTNR1A | |
| SCHEMBL7432703 | 0.83 | KDM4E (0.47) | HTR1AHTR1DHTR2CMTNR1AKDM4E | |
| SCHEMBL7019210 | 0.82 | MTNR1A (0.49) | HTR1AHTR1DHTR2CSIRT1MTNR1A | |
| SCHEMBL8695136 | 0.80 | MTNR1A (0.67) | ALDH1A1TSHRMTNR1AKMT2ALMNA | |
| SCHEMBL2269511 | 0.79 | MTNR1A (0.51) | HTR1AHTR1DHTR2CSIRT1ALDH1A1 | |
| SCHEMBL5762073 | 0.79 | MAOB (0.53) | KDM4EMAOB | |
| SCHEMBL2267233 | 0.78 | NPC1 (0.49) | SIRT1ALDH1A1TSHRNPSR1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721276-A | TREATING DISORDERS OF MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1998-02-24 | — | — | US | disclosed |