Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30499193 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP11B1CYP11B2GAAMAPT | |
| SCHEMBL29436325 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTALDH1A3 | |
| SCHEMBL116316 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTALDH1A3 | |
| SCHEMBL29952839 | 0.77 | CYP1A2 (0.39) | ALDH1A1MAPTALDH1A3 | |
| SCHEMBL8544546 | 0.77 | CYP1A2 (0.39) | ALDH1A1MAPTALDH1A3 | |
| SCHEMBL7981808 | 0.75 | ALDH1A3 (0.37) | ALDH1A1LMNAALDH1A3MAPK1 | |
| SCHEMBL8545176 | 0.75 | KDM4E (0.43) | ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL15652088 | 0.75 | PIK3CD (0.43) | ALDH1A1MAPT | |
| SCHEMBL335730 | 0.75 | ALDH1A3 (0.41) | ALDH1A1MAPTLMNAALDH1A3MAPK1 | |
| SCHEMBL875527 | 0.75 | POLB (0.38) | ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179032-A1 | HETEROCYCLIC INHIBITORS OF GLUT9 FOR TREATMENT OF DISEASE | HORIZON THERAPEUTICS IRELAND DAC (IE) | 2025-06-05 | — | — | US | disclosed |
| CN-119013265-A | GLUT9 heterocyclic inhibitors for the treatment of disease | 爱尔兰好利恩治疗有限公司 | 2024-11-22 | — | — | CN | disclosed |
| EP-4460496-A1 | HETEROCYCLIC INHIBITORS OF GLUT9 FOR TREATMENT OF DISEASE | Horizon Therapeutics Ireland DAC (IE) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023131868-A1 | HETEROCYCLIC INHIBITORS OF GLUT9 FOR TREATMENT OF DISEASE | HORIZON THERAPEUTICS IRELAND DAC (IE) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131868-A1 | HETEROCYCLIC INHIBITORS OF GLUT9 FOR TREATMENT OF DISEASE | HORIZON THERAPEUTICS IRELAND DAC (IE) | 2023-07-13 | — | — | WO | disclosed |
| US-20100286131-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| US-20100286131-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| EP-1301493-A2 | HETEROCYCLE CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004444-A2 | HETEROCYCLE CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-01-17 | — | — | WO | disclosed |
| US-4925947-A | AGRICULTURAL USE, SENSITIVE TO CROPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| US-4555575-A | CHLORINATION OF A DISUBSTITUTED METHYL PYRIDINE HYDROCHLORIDE SALT | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1985-11-26 | — | — | US | disclosed |
| US-4508907-A | 2,3-Dichloro-5-trichloromethylpyridine | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1985-04-02 | — | — | US | disclosed |
| EP-0107866-A2 | Trihalomethylpyridine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-09 | — | — | EP | disclosed |
| US-4324627-A | CHLORINATION OF 3-METHYLPYRIDINE UNDER INFLUENCE OF ULTRA VIOLET LIGHT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-04-13 | — | — | US | disclosed |
| US-4317913-A | Herbicidal pyridine compounds | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-03-02 | — | — | US | disclosed |
| EP-0028870-A1 | Phenoxypyridine compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-05-20 | — | — | EP | disclosed |
| EP-0021453-A2 | 2-Chloro-5-trichloromethylpyridine | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-01-07 | — | — | EP | disclosed |
| EP-0001473-A2 | Herbicidal halogenomethyl--pyridyloxy-phenoxy-alkanecarboxylic acids and derivatives, and processes of controlling unwanted plants therewith | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-04-18 | — | — | EP | disclosed |
| WO-1979000094-A1 | HERBICIDAL PYRIDINE COMPOUNDS | ICI LTD (GB) | 1979-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286131-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2B | ALDH1A1 1257/4885CYP11B1 2071/4885CYP11B2 2717/4885 |
| US-20250179032-A1 | HETEROCYCLIC INHIBITORS OF GLUT9 FOR TREATMENT OF DISEASE | SLC2A9, SLC2A1, SLC2A8 | ALDH1A1 745/4885CYP11B1 2089/4885CYP11B2 2395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.