SCHEMBL7101252

SCHEMBL7101252

C=CC(=O)Oc1ccc(NC(C)=O)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.70
MEN1 O00255 4/20 0.70
NPSR1 Q6W5P4 1/20 0.60
ALDH1A1 P00352 4/20 0.56
MAPT P10636 1/20 0.56
SMN1; SMN2 Q16637 4/20 0.55
HSD17B10 Q99714 3/20 0.55
TDP1 Q9NUW8 2/20 0.54
LMNA P02545 1/20 0.54
CYP1A2 P05177 1/20 0.54
TGM2 P21980 1/20 0.53
HPGD P15428 3/20 0.53
OPRK1 P41145 1/20 0.53
HTT P42858 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA9 Q16790 1/20 0.51
THRB P10828 1/20 0.51
TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27832386 0.85 KMT2A (0.75) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL17253347 0.84 KMT2A (0.72) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL14808444 0.83 KMT2A (1.00) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL16692528 0.82 KMT2A (0.60) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL28804310 0.82 ALDH1A1 (0.53) KMT2AMEN1ALDH1A1MAPTHSD17B10
SCHEMBL10086611 0.81 THRB (0.53) KMT2AMEN1NPSR1ALDH1A1MAPT
Diacetamate SCHEMBL863106 0.81 KMT2A (0.81) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL2587522 0.80 THRB (0.64) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL20769833 0.80 KMT2A (0.79) KMT2AMEN1NPSR1ALDH1A1MAPT
SCHEMBL11620304 0.80 THRB (0.61) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1339665-A1 NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS Nicox S.A. (FR) 2003-09-03 EP claimed
WO-2002030866-A1 NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS NICOX S.A. (FR) 2002-04-18 WO claimed
US-10042258-B2 Composition for forming a resist upper-layer film and method for producing a semiconductor device using the composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-08-07 US disclosed
US-10042258-B2 Composition for forming a resist upper-layer film and method for producing a semiconductor device using the composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-08-07 US disclosed
US-20170205711-A1 COMPOSITION FOR FORMING A RESIST UPPER-LAYER FILM AND METHOD FOR PRODUCING A SEMICONDUCTOR DEVICE USING THE COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-07-20 US disclosed
US-20170205711-A1 COMPOSITION FOR FORMING A RESIST UPPER-LAYER FILM AND METHOD FOR PRODUCING A SEMICONDUCTOR DEVICE USING THE COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-07-20 US disclosed