Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502103 | 0.93 | NPC1 (0.66) | MAPTKMT2ALMNANPSR1RAB9A | |
| SCHEMBL27704684 | 0.92 | ALDH1A1 (0.59) | MAPTKMT2ALMNANPSR1RAB9A | |
| SCHEMBL8458703 | 0.87 | NPC1 (0.59) | MAPTKMT2ALMNANPSR1RAB9A | |
| SCHEMBL8458977 | 0.87 | NPC1 (0.59) | MAPTKMT2ALMNANPSR1RAB9A | |
| SCHEMBL8460805 | 0.86 | BACE1 (0.57) | MAPTKMT2ALMNANPSR1RAB9A | |
| SCHEMBL7102473 | 0.86 | NPC1 (0.57) | MAPTKMT2ALMNANPSR1RAB9A | |
| SCHEMBL4447795 | 0.86 | KMT2A (0.64) | MAPTKMT2ALMNANPSR1RAB9A | |
| SCHEMBL8460808 | 0.85 | ALDH1A1 (0.57) | MAPTKMT2ALMNANPSR1RAB9A | |
| SCHEMBL8716568 | 0.83 | NPC1 (0.55) | MAPTKMT2ALMNANPSR1RAB9A | |
| SCHEMBL8461753 | 0.83 | BACE1 (0.57) | MAPTKMT2ANPSR1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838464-B1 | Substituted benzo(b)thiophene compounds having activity as selective estrogen receptor modulators | LILLY CO ELI (US) | 2003-09-10 | — | — | EP | claimed |