Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041989 | 0.99 | KMT2A (0.45) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL7046695 | 0.86 | ALDH1A1 (0.34) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL7044554 | 0.86 | ALDH1A1 (0.34) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL7047413 | 0.82 | PTGS2 (0.37) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL7044725 | 0.76 | L3MBTL1 (0.34) | MAPTSMN1; SMN2ALDH1A1LMNARAB9A | |
| SCHEMBL7101567 | 0.71 | KMT2A (0.41) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL7041986 | 0.71 | KMT2A (0.43) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL7049035 | 0.70 | GRM5 (0.34) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL7043673 | 0.70 | LMNA (0.50) | KMT2AMAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL7645268 | 0.70 | BTK (0.33) | KMT2AMEN1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064096-A9 | METHODS OF USING PYRIMIDINE-BASED ANTIVIRAL AGENTS | TULARIK INC (US) | 2003-10-16 | — | — | WO | disclosed |
| WO-2002064096-A2 | METHODS OF USING PYRIMIDINE-BASED ANTIVIRAL AGENTS | TULARIK INC. (US) | 2002-08-22 | — | — | WO | disclosed |