Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PRKCG | P05129 | 4/20 | 0.42 |
| ▸ | PRKCB | P05771 | 4/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | PRKACA | P17612 | 2/20 | 0.42 |
| ▸ | PRKACG | P22612 | 2/20 | 0.42 |
| ▸ | PRKACB | P22694 | 2/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101760 | 1.00 | KDM4E (0.48) | KDM4EPRKCGPRKCBPRKCDPRKCE | |
| SCHEMBL7107509 | 0.85 | KDM4E (0.47) | KDM4EPRKCGPRKCBPRKCDPRKCE | |
| SCHEMBL7107511 | 0.83 | KDM4E (0.45) | KDM4EPRKCGPRKCBPRKCDPRKCE | |
| SCHEMBL7107514 | 0.83 | KDM4E (0.45) | KDM4EPRKCGPRKCBPRKCDPRKCE | |
| SCHEMBL6358461 | 0.75 | TAS1R3 (0.42) | CTSS | |
| SCHEMBL4870913 | 0.74 | CHRM1 (0.53) | MAPTALDH1A1CHRM1CHRM2CHRM4 | |
| SCHEMBL4868985 | 0.74 | CHRM1 (0.53) | MAPTALDH1A1CHRM1CHRM2CHRM4 | |
| SCHEMBL4868987 | 0.74 | CHRM1 (0.53) | MAPTALDH1A1CHRM1CHRM2CHRM4 | |
| SCHEMBL7149111 | 0.73 | GAA (0.43) | KDM4EMAPTALDH1A1GAAHTT | |
| SCHEMBL5115602 | 0.69 | CHRM1 (0.56) | CHRM1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923543-B1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2003-09-24 | — | — | EP | disclosed |
| US-6083986-A | Potassium channel inhibitors | ICAGEN, INC. (US) | 2000-07-04 | — | — | US | disclosed |