Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 4/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27574737 | 1.00 | ZDHHC7 (0.45) | ZDHHC7ABCB1CA1CA2USP2 | |
| SCHEMBL27552552 | 0.89 | ZDHHC7 (0.36) | ZDHHC7GPR84FFAR1FFAR4 | |
| SCHEMBL7106845 | 0.89 | ZDHHC7 (0.36) | ZDHHC7GPR84FFAR1FFAR4 | |
| SCHEMBL7101825 | 0.87 | GPR84 (0.42) | GPR84FFAR1FFAR4 | |
| SCHEMBL29164319 | 0.86 | ZDHHC7 (0.39) | ZDHHC7ABCB1CA1CA2USP2 | |
| SCHEMBL7108501 | 0.81 | GPR84 (0.39) | CA2GPR84FFAR1FFAR4 | |
| SCHEMBL29164317 | 0.79 | ZDHHC7 (0.39) | ZDHHC7ABCB1 | |
| SCHEMBL29164318 | 0.79 | ZDHHC7 (0.39) | ZDHHC7ABCB1 | |
| SCHEMBL9457090 | 0.78 | GPR84 (0.54) | ZDHHC7ABCB1CA1CA2USP2 | |
| SCHEMBL28769950 | 0.78 | GPR84 (0.54) | ZDHHC7ABCB1CA1CA2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127886-B1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2one | HOFFMANN LA ROCHE (CH) | 2003-05-07 | — | — | EP | claimed |
| CN-1319596-A | Synthesis of 3,6-dialkyl 5,6-dihydro-4-hydroxide-2H-pyran-2-ketone | HOFFMANN LA ROCHE (CH) | 2001-10-31 | — | — | CN | disclosed |