Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101825 | 0.91 | GPR84 (0.42) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL7101909 | 0.81 | ZDHHC7 (0.45) | GPR84FFAR1CA2FFAR4 | |
| SCHEMBL27574737 | 0.81 | ZDHHC7 (0.45) | GPR84FFAR1CA2FFAR4 | |
| SCHEMBL27552552 | 0.81 | ZDHHC7 (0.36) | GPR84FFAR1MAPTFFAR4 | |
| SCHEMBL7106845 | 0.81 | ZDHHC7 (0.36) | GPR84FFAR1MAPTFFAR4 | |
| SCHEMBL7103007 | 0.81 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL7103003 | 0.81 | GPR84 (0.53) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28072157 | 0.79 | GPR84 (0.38) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL7104806 | 0.77 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL7103210 | 0.76 | ALDH1A1 (0.41) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127886-B1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2one | HOFFMANN LA ROCHE (CH) | 2003-05-07 | — | — | EP | claimed |