Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27552552 | 1.00 | ZDHHC7 (0.36) | ZDHHC7GPR84TDP1MEN1KMT2A | |
| SCHEMBL7101909 | 0.89 | ZDHHC7 (0.45) | ZDHHC7GPR84FFAR1FFAR4 | |
| SCHEMBL27574737 | 0.89 | ZDHHC7 (0.45) | ZDHHC7GPR84FFAR1FFAR4 | |
| SCHEMBL7101825 | 0.87 | GPR84 (0.42) | GPR84TDP1MEN1KMT2AMAPT | |
| SCHEMBL11967106 | 0.86 | ZDHHC7 (0.34) | ZDHHC7GPR84TDP1MEN1KMT2A | |
| SCHEMBL7108501 | 0.81 | GPR84 (0.39) | GPR84MAPTFFAR1FFAR4 | |
| SCHEMBL27506299 | 0.78 | GPR84 (0.54) | ZDHHC7GPR84MEN1KMT2AFFAR1 | |
| SCHEMBL7101917 | 0.78 | GPR84 (0.54) | ZDHHC7GPR84MEN1KMT2AFFAR1 | |
| SCHEMBL7103007 | 0.77 | GPR84 (0.53) | GPR84MEN1KMT2AMAPTFFAR1 | |
| SCHEMBL7103003 | 0.77 | GPR84 (0.53) | GPR84MEN1KMT2AMAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127886-B1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2one | HOFFMANN LA ROCHE (CH) | 2003-05-07 | — | — | EP | claimed |
| CN-1319596-A | Synthesis of 3,6-dialkyl 5,6-dihydro-4-hydroxide-2H-pyran-2-ketone | HOFFMANN LA ROCHE (CH) | 2001-10-31 | — | — | CN | disclosed |