Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105614 | 1.00 | USP2 (0.41) | USP2TSHRCYP3A4CYP2C19FDPS | |
| SCHEMBL4556660 | 0.98 | TSHR (0.39) | USP2TSHRCYP3A4CYP2C19FDPS | |
| SCHEMBL7108350 | 0.94 | FDPS (0.36) | USP2TSHRCYP3A4CYP2C19FDPS | |
| SCHEMBL9957482 | 0.83 | USP2 (0.37) | USP2TSHRCYP3A4CYP2C19 | |
| SCHEMBL10614529 | 0.81 | USP2 (0.41) | USP2TSHRDPP4 | |
| SCHEMBL3787650 | 0.79 | MAOA (0.44) | CYP3A4CYP2C19ALOX15CASP1CASP7 | |
| SCHEMBL10191864 | 0.78 | ALDH1A1 (0.44) | USP2TSHR | |
| SCHEMBL10192225 | 0.78 | ALDH1A1 (0.44) | USP2TSHR | |
| Ammonia Solution, Strong SCHEMBL14343978 | 0.78 | MAOA (0.42) | CYP3A4CYP2C19SIGMAR1 | |
| SCHEMBL5348277 | 0.78 | GRIN2B (0.41) | USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942010-B1 | Transition metal compounds, catalyst components and catalysts for olefin polymerization, and process for producing olefinic polymer | SUMITOMO CHEMICAL CO (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-6500909-B2 | CONTAINING NICKEL, PALLADIUM, RHODIUM, RUTHENIUM, OR COBALT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-31 | — | — | US | disclosed |
| US-20010027162-A1 | Transition metal compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefinic polymer | HIRAHATA WATARU (JP) | 2001-10-04 | — | — | US | disclosed |
| US-6242377-B1 | POLYMERIZATION IN PRESENCE OF BISOXAZOLINE WITH NICKEL, COBALT, PALLADIUM, RHODIUM, RUTHENIUM, ALUMINUM AND BORON COMPLEXES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0942010-A1 | Transition metal compounds, catalyst components and catalysts for olefin polymerization, and process for producing olefinic polymers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-4155935-A | Benzylamine analgesics | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-05-22 | — | — | US | disclosed |
| US-4017637-A | Benzylamine analgesics | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-04-12 | — | — | US | disclosed |
| US-3928626-A | Benzylamine analgesics | AMERICAN HOME PROD | 1975-12-23 | — | — | US | disclosed |