Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 11/20 | 0.38 |
| ▸ | MASP2 | O00187 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7145270 | 0.99 | OPRK1 (0.40) | OPRK1KCNH2F2MASP2BACE1 | |
| SCHEMBL7106700 | 0.86 | F2 (0.39) | F2MASP2PLGPRSS1 | |
| SCHEMBL7105021 | 0.80 | F2 (0.49) | F2 | |
| Hydrochloric Acid SCHEMBL7147052 | 0.80 | F2 (0.51) | F2 | |
| Hydrochloric Acid SCHEMBL7379102 | 0.67 | PLG (0.39) | F2F10PLGPLATPRSS1 | |
| SCHEMBL8809131 | 0.66 | HTR2C (0.64) | F2MASP2HTR2CHTR2BHDAC3 | |
| SCHEMBL7144656 | 0.66 | F2 (0.45) | F2PLGPRSS1 | |
| Hydrochloric Acid SCHEMBL8702542 | 0.66 | F2 (0.42) | F2MASP2CTSC | |
| Hydrochloric Acid SCHEMBL5900833 | 0.65 | HTR2C (0.62) | F2MASP2HTR2CHTR2BHDAC3 | |
| Hydrochloric Acid SCHEMBL5900838 | 0.65 | HTR2C (0.62) | F2MASP2HTR2CHTR2BHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |