Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.39 |
| ▸ | MASP2 | O00187 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102852 | 0.86 | OPRK1 (0.40) | F2MASP2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL7145270 | 0.86 | OPRK1 (0.40) | F2MASP2 | |
| SCHEMBL7105021 | 0.82 | F2 (0.49) | F2 | |
| Hydrochloric Acid SCHEMBL7147052 | 0.81 | F2 (0.51) | F2 | |
| SCHEMBL7144656 | 0.70 | F2 (0.45) | F2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL7148146 | 0.70 | F2 (0.46) | F2PRSS1PLG | |
| SCHEMBL8809131 | 0.67 | HTR2C (0.64) | F2MASP2KDM4E | |
| Hydrochloric Acid SCHEMBL5900833 | 0.66 | HTR2C (0.62) | F2MASP2KDM4E | |
| Hydrochloric Acid SCHEMBL5900838 | 0.66 | HTR2C (0.62) | F2MASP2KDM4E | |
| SCHEMBL1162982 | 0.66 | MAOA (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |