Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639578 | 0.80 | RELA (0.40) | ALDH1A1TSHRTP53TDP1RELA | |
| Styrene SCHEMBL2862346 | 0.77 | ALDH1A1 (0.78) | ALDH1A1TSHRTP53TDP1RELA | |
| Styrene SCHEMBL1567316 | 0.75 | ALDH1A1 (0.74) | ALDH1A1TSHRTP53TDP1RELA | |
| Styrene SCHEMBL28631449 | 0.75 | ALDH1A1 (0.74) | ALDH1A1TSHRTP53TDP1GRM5 | |
| Styrene SCHEMBL28019103 | 0.75 | ALDH1A1 (0.74) | ALDH1A1TSHRTP53TDP1RELA | |
| Styrene SCHEMBL27910207 | 0.75 | ALDH1A1 (0.74) | ALDH1A1TSHRTP53TDP1RELA | |
| Styrene SCHEMBL29362209 | 0.74 | — | — | |
| O-Xylene SCHEMBL10383145 | 0.74 | ACHE (0.46) | ALDH1A1TSHRTDP1 | |
| Styrene SCHEMBL28623488 | 0.73 | ALDH1A1 (0.70) | ALDH1A1TSHRTP53TDP1RELA | |
| Styrene SCHEMBL28457080 | 0.73 | ALDH1A1 (0.70) | ALDH1A1TSHRTP53TDP1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752995-B1 | IMPROVED METHOD OF PREPARATION OF LITHIUM ALKYLAMIDES | FMC CORP (US) | 2003-09-17 | — | — | EP | disclosed |
| EP-0752995-A4 | IMPROVED METHOD OF PREPARATION OF LITHIUM ALKYLAMIDES | FMC CORP (US) | 1999-06-09 | — | — | EP | disclosed |
| EP-0752995-A1 | IMPROVED METHOD OF PREPARATION OF LITHIUM ALKYLAMIDES | FMC CORPORATION (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995023803-A9 | IMPROVED METHOD OF PREPARATION OF LITHIUM ALKYLAMIDES | — | 1996-11-14 | — | — | WO | disclosed |
| US-5493038-A | REACTING LITHIUM METAL WITH ALKYLAMINE IN ETHEREAL SOLVENT IN PRESENCE OF ELECTRON CARRIER UNDER INERT ATMOSPHERE AT ELEVATED TEMPERATURES, COOLING, SEPARATING PRODUCT | FMC CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |
| WO-1995023803-A1 | IMPROVED METHOD OF PREPARATION OF LITHIUM ALKYLAMIDES | FMC CORPORATION (US) | 1995-09-08 | — | — | WO | disclosed |