SCHEMBL7103045

SCHEMBL7103045

N#CCc1c(F)ccc(C(F)(F)F)c1F

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.38
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
AR P10275 2/20 0.32
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29517820 0.80 EGFR (0.32) MEN1MAPTHPGDKMT2A
SCHEMBL7104591 0.80 EGFR (0.32) MEN1MAPTHPGDKMT2A
SCHEMBL24147004 0.79 RXRA (0.35) KIF11RXRARXRBRXRGMAPT
SCHEMBL954890 0.78 SLC6A2 (0.38) KIF11RXRARXRBRXRGMEN1
SCHEMBL25982749 0.78 KIF11 (0.34) KIF11RXRARXRBRXRG
SCHEMBL5929239 0.76 RXRA (0.42) KIF11RXRARXRBRXRGMEN1
SCHEMBL952788 0.74 AR (0.41) RXRARXRBRXRGARCTSS
SCHEMBL2077254 0.73 MPO (0.35) HPGD
SCHEMBL955712 0.73 HTT (0.33)
SCHEMBL19995552 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6528657-B2 For use in electroluminescence light emission element and can emit lights of various colors when an energy such as electric energy or electromagnetic energy is applied thereto TAIHO INDUSTRIES CO., LTD. (JP) 2003-03-04 US disclosed
US-20030023099-A1 Novel fluorescent carbazole derivative HIROSE ENGINEERING CO., LTD. (JP) 2003-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030023099-A1 Novel fluorescent carbazole derivative CBR3, AANAT, SIRT3 KIF11 1198/4885RXRA 4472/4885RXRB 4519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.