Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655310 | 0.80 | TP53 (0.45) | TP53CA2TSHRSMN1; SMN2FDPS | |
| SCHEMBL27951233 | 0.80 | CA2 (0.41) | TP53CA2CA1CA12CA7 | |
| SCHEMBL23181465 | 0.77 | TP53 (0.38) | TP53CA2TSHRSMN1; SMN2FDPS | |
| SCHEMBL7103231 | 0.76 | TP53 (0.32) | TP53CA2TSHRSMN1; SMN2FDPS | |
| SCHEMBL11250128 | 0.76 | ALDH1A1 (0.46) | CA2TSHRSMN1; SMN2MAPK1CA1 | |
| SCHEMBL2021649 | 0.75 | — | — | |
| SCHEMBL4540450 | 0.74 | DNM1 (0.45) | TP53CA2TSHRSMN1; SMN2FDPS | |
| SCHEMBL10785516 | 0.72 | TP53 (0.32) | TP53 | |
| SCHEMBL27574241 | 0.72 | DNM1 (0.43) | TP53CA2TSHRSMN1; SMN2FDPS | |
| Phosphoric Acid SCHEMBL11360803 | 0.71 | FDPS (0.56) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-1020437-A1 | PROCESS FOR PRODUCING HALOGENOALKYLSULFONAMIDE DERIVATIVES | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |