Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103246 | 0.91 | RELA (0.39) | RELATSHRTDP1CA2ALDH1A1 | |
| SCHEMBL9233467 | 0.85 | — | — | |
| SCHEMBL6827393 | 0.82 | CA1 (0.46) | RELATSHRTDP1CA12CA1 | |
| SCHEMBL3816066 | 0.80 | CA1 (0.52) | RELATSHRTDP1CA12CA1 | |
| SCHEMBL2010127 | 0.80 | CA1 (0.44) | RELACA12CA1CA2CA7 | |
| SCHEMBL7432483 | 0.78 | RELA (0.50) | RELACA12CA1CA2CA7 | |
| SCHEMBL7691856 | 0.76 | RELA (0.53) | RELACA1CA2 | |
| SCHEMBL11883426 | 0.76 | RELA (0.53) | RELACA1CA2 | |
| SCHEMBL21236089 | 0.76 | RELA (0.49) | RELATSHRCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL28232067 | 0.76 | RELA (0.49) | RELACA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266814-B2 | Use of nitrooxy organic molecules in feed for reducing methane emission in ruminants, and/or to improve ruminant performance | DSM IP ASSETS B.V. (NL) | 2016-02-23 | — | — | US | disclosed |
| US-20150376113-A1 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS BV (NL) | 2015-12-31 | — | — | US | disclosed |
| US-20140147529-A1 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS B.V. (NL) | 2014-05-29 | — | — | US | disclosed |
| WO-2012084629-A1 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS B.V. (NL) | 2012-06-28 | — | — | WO | disclosed |
| US-6743923-B2 | A BENZYLIDENE DERIVATIVES USED FOR OSTEOCLAST FORMATION INHIBITION, A NITROGEN MONOXIDE PRODUCTION INHIBITION, AND A TRANSCRIPTION FACTOR NF KAPPA B SUPRESSING AGENT | SHIONOGI & CO., LTD. (JP) | 2004-06-01 | — | — | US | disclosed |
| CN-1127492-C | Antirheumatic | SHIONOJI & CO LTD (JP) | 2003-11-12 | — | — | CN | disclosed |
| US-6632452-B1 | Antiinflammatory agent or an antioxidant; adding an organic acid or an inorganic acid to tablet; (E)-2-ethyl-5-(3,5-di-tert-butyl-4-hydroxy)benzyliden-1,2-isothiazolidin-1,1-dioxide | SHIONOGI & CO., LTD. (JP) | 2003-10-14 | — | — | US | disclosed |
| US-20030125364-A1 | Antirheumatic agent | MATSUMOTO SAICHI (JP) | 2003-07-03 | — | — | US | disclosed |
| US-6525081-B1 | Inhibiting osteoclast formation and nitrogen monoxide production; suppressing transcription factor NF kappa B | SHIONOGI & CO., LTD. (JP) | 2003-02-25 | — | — | US | disclosed |
| CN-1343119-A | Medicinal composition for delaying color change of phenolic hydroxyl compound | SHIONOGI & CO (JP) | 2002-04-03 | — | — | CN | disclosed |
| EP-1151750-A1 | MEDICINAL COMPOSITIONS RETARDED IN THE DISCOLORATION OF PHENOLIC HYDROXYL COMPOUNDS | SHIONOGI & CO., LTD. (JP) | 2001-11-07 | — | — | EP | disclosed |
| CN-1283194-A | Antirheumatic | SHIONOJI & CO LTD (JP) | 2001-02-07 | — | — | CN | disclosed |
| EP-1026162-A1 | ANTIRHEUMATIC | SHIONOGI & CO., LTD. (JP) | 2000-08-09 | — | — | EP | disclosed |
| EP-0595546-B1 | Benzylidene derivatives | SHIONOGI & CO (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5418230-A | Antiinflammatory | SHIONOGI & CO., LTD. (JP) | 1995-05-23 | — | — | US | disclosed |
| EP-0595546-A1 | Benzylidene derivatives | SHIONOGI & CO., LTD. (JP) | 1994-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125364-A1 | Antirheumatic agent | IL1A, IL1B, IL17A | RELA 279/4885TSHR 3434/4885TDP1 2154/4885 |
| US-20140147529-A1 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | MLNR, PIGS, MTR | RELA 1498/4885TSHR 568/4885TDP1 3279/4885 |
| US-20150376113-A1 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | MLNR, PIGS, MTR | RELA 1498/4885TSHR 568/4885TDP1 3279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.