Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483396 | 0.90 | POLB (0.44) | POLBGAALMNAALOX5FOLH1 | |
| SCHEMBL6492056 | 0.86 | POLB (0.46) | POLBGAALMNAALOX5CETP | |
| SCHEMBL6784313 | 0.78 | POLB (0.50) | POLBGAAMAPTSMN1; SMN2ALOX5 | |
| SCHEMBL8330920 | 0.76 | LMNA (0.53) | LMNAMAPTSMN1; SMN2ALOX5 | |
| SCHEMBL15778088 | 0.75 | POLB (0.52) | POLBGAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8330922 | 0.73 | PPARG (0.50) | POLBLMNAMAPTSMN1; SMN2ALOX5 | |
| SCHEMBL331957 | 0.73 | CYP3A4 (0.38) | POLBGAALMNAMAPT | |
| SCHEMBL1239980 | 0.73 | POLB (0.52) | POLBGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2023736 | 0.72 | LMNA (0.56) | LMNAMAPTSMN1; SMN2ALOX5 | |
| SCHEMBL7110468 | 0.72 | ALDH1A1 (0.41) | LPAR1LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030008361-A1 | Process for the preparation of substituted 3-phenyl-propanoic acid esters and substituted 3-phenyl-propanoic acids | EBDRUP SOREN (DK) | 2003-01-09 | — | — | US | disclosed |
| CN-1375013-A | Process for the preparation of substituted 3-phenyl-propanoic acid esters and substituted 3-phenyl-propanoic acids | NOVO NORDISK AS (DK) | 2002-10-16 | — | — | CN | disclosed |
| EP-1206565-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-PHENYL-PROPANOIC ACID ESTERS AND SUBSTITUTED 3-PHENYL-PROPANOIC ACIDS | NOVO NORDISK A/S (DK) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001011073-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-PHENYL-PROPANOIC ACID ESTERS AND SUBSTITUTED 3-PHENYL-PROPANOIC ACIDS | NOVO NORDISK A/S (DK) | 2001-02-15 | — | — | WO | disclosed |