SCHEMBL710342

SCHEMBL710342

COC(=O)c1cc(O)cc(CO)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.68
CA1 P00915 5/20 0.68
CA2 P00918 5/20 0.68
CA7 P43166 5/20 0.68
CA9 Q16790 5/20 0.68
CA14 Q9ULX7 5/20 0.68
LMNA P02545 2/20 0.50
KDM4E B2RXH2 2/20 0.50
XDH P47989 2/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
NFKB1 P19838 1/20 0.50
GFER P55789 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
FUT7 Q11130 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ACHE P22303 1/20 0.50
HPGD P15428 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2650418 0.88 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL762861 0.88 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL90400 0.87 CA1 (0.70) CA12CA1CA2CA7CA9
SCHEMBL16951249 0.83 PRKCA (0.49) CA12CA1CA2CA7CA9
SCHEMBL2161045 0.83 SLC7A5 (0.62) CA12CA1CA2CA7CA9
SCHEMBL2668277 0.82 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL46504 0.82 CA12 (0.91) CA12CA1CA2CA7CA9
Methyl 3,5-Dihydroxybenzoate SCHEMBL38869 0.82 CA1 (1.00) CA12CA1CA2CA7CA9
SCHEMBL13898816 0.81 SLC7A5 (0.49) CA12CA1CA2CA7CA9
SCHEMBL475791 0.81 SLC7A5 (0.49) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124767-B2 Luminescence biotin-transition metal complex conjugate, and method of amplifying signal using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-02-28 US disclosed
US-8124767-B2 Luminescence biotin-transition metal complex conjugate, and method of amplifying signal using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-02-28 US disclosed
US-8124767-B2 Luminescence biotin-transition metal complex conjugate, and method of amplifying signal using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-02-28 US disclosed
EP-1646608-B1 TRICYCLIC DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM JE IL PHARMACEUTICAL CO LTD (KR) 2011-03-02 EP disclosed
US-20090209048-A1 Luminescence Biotin-Transition Metal Complex Conjugate, and Method of Amplifying Signal Using the Same SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-08-20 US disclosed
US-20090209048-A1 Luminescence Biotin-Transition Metal Complex Conjugate, and Method of Amplifying Signal Using the Same SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-08-20 US disclosed
US-20090209048-A1 Luminescence Biotin-Transition Metal Complex Conjugate, and Method of Amplifying Signal Using the Same SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-08-20 US disclosed
US-20070179143-A1 Tricyclic derivatives or pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containing them JE IL PHARMACEUTICAL CO., LTD. (KR) 2007-08-02 US disclosed
US-20070179143-A1 Tricyclic derivatives or pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containing them JE IL PHARMACEUTICAL CO., LTD. (KR) 2007-08-02 US disclosed
WO-2007058504-A1 NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME LG LIFE SCIENCES, LTD. (KR) 2007-05-24 WO disclosed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070179143-A1 Tricyclic derivatives or pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containing them VEGFA, TUBB3, TUBA3C CA12 1330/4885CA1 1776/4885CA2 401/4885
US-20090209048-A1 Luminescence Biotin-Transition Metal Complex Conjugate, and Method of Amplifying Signal Using the Same BTD, HLCS, BPGM CA12 2975/4885CA1 3691/4885CA2 2193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.