Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27740369 | 0.82 | NPC1 (0.40) | XDHP2RX7ARTSHR | |
| SCHEMBL15129482 | 0.82 | PNMT (0.54) | XDHP2RX7TSHR | |
| SCHEMBL11240306 | 0.82 | XDH (0.41) | XDHHTR2AHTR2CP2RX7AR | |
| SCHEMBL16957570 | 0.81 | XDH (0.41) | XDHGABRA1GABRB2P2RX7AR | |
| SCHEMBL8878530 | 0.80 | XDH (0.40) | XDHHTR2AHTR2CP2RX7AR | |
| SCHEMBL16960269 | 0.80 | XDH (0.40) | XDHHTR2AHTR2CP2RX7AR | |
| SCHEMBL16953236 | 0.80 | XDH (0.43) | XDHP2RX7ARTSHRCA1 | |
| SCHEMBL16952111 | 0.80 | GABRA1 (0.42) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| SCHEMBL18007091 | 0.79 | SLC6A4 (0.42) | XDHHTR2AP2RX7TSHR | |
| SCHEMBL106062 | 0.79 | TSHR (0.50) | GABRA1GABRB2ARTSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355909-A2 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002062795-A2 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | MITSUBISHI PHARMA CORPORATION (JP) | 2002-08-15 | — | — | WO | disclosed |