SCHEMBL7103671

SCHEMBL7103671

COC(=O)Cc1ccc(-c2ccccc2)cc1CC(=O)OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 2/20 0.56
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
KMT2A Q03164 1/20 0.49
MAPK1 P28482 1/20 0.46
DCLRE1A Q6PJP8 1/20 0.45
DCLRE1B Q9H816 1/20 0.45
CFD P00746 1/20 0.44
EGFR P00533 1/20 0.44
CYP2C19 P33261 1/20 0.44
NPC1 O15118 1/20 0.44
PKM P14618 1/20 0.44
HPGD P15428 1/20 0.44
NFKB1 P19838 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17105795 0.91 ACLY (0.46) ACLYKDM4EMEN1ALDH1A1MAPT
SCHEMBL27694509 0.87 CYP1A2 (0.51) ACLYKDM4EMEN1ALDH1A1MAPT
SCHEMBL27141469 0.86 ACLY (0.56) ACLYKDM4EMEN1ALDH1A1MAPT
SCHEMBL10713766 0.86 ACLY (0.53) ACLYKDM4EMEN1ALDH1A1MAPT
SCHEMBL6862344 0.84 L3MBTL1 (0.49) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL28321278 0.81 ACLY (0.48) ACLYMEN1ALDH1A1KMT2AEGFR
SCHEMBL5156156 0.80 PTGS1 (0.59) DCLRE1ADCLRE1BCFDPTGS1HTT
SCHEMBL3357146 0.80 GAA (0.55) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL1554320 0.80 KDM4E (0.53) KDM4EALDH1A1MAPTCFDEGFR
SCHEMBL1428025 0.79 LMNA (0.62) KDM4EMEN1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6800706-B1 TRANSPARENT, LOW-TEMPERATURE HEAT-SEALABILITY AND WEAR RESISTANCE; WRAPPING AND PACKAGING FILMS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-10-05 US disclosed
EP-1153944-A1 PROPYLENE POLYMER, MOLDED OBJECT THEREOF, AND PROCESS FOR PRODUCING PROPYLENE POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-11-14 EP disclosed