Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25169 | 0.87 | CES1 (0.58) | LMNAABCC4GAATSHRPTGS1 | |
| Bicarbonate SCHEMBL10938525 | 0.85 | CES1 (0.56) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL12836715 | 0.82 | LMNA (0.62) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL26084 | 0.79 | LMNA (1.00) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL11879591 | 0.79 | LMNA (0.75) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL23666036 | 0.78 | LMNA (0.56) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL15309802 | 0.78 | ALDH1A1 (0.52) | GAATSHRPTGS1KMT2AMEN1 | |
| Felbinac SCHEMBL384892 | 0.77 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL7410335 | 0.77 | LMNA (0.72) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL8844919 | 0.77 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097664-A2 | NON-COVALENT INHIBITORS OF CYSTEINE PROTEASES WITH ATRIPEPTIDE BACKBONE | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2003-11-27 | — | — | WO | disclosed |