Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038732 | 0.87 | TRPV4 (0.36) | TRPV4ALDH1A1HSD17B10 | |
| SCHEMBL9614361 | 0.86 | ALDH1A1 (0.42) | CYP1A2ALDH1A1THRBHPGDHSD17B10 | |
| SCHEMBL586454 | 0.85 | AURKA (0.32) | CYP1A2ALDH1A1THRBHPGDHSD17B10 | |
| SCHEMBL1285825 | 0.84 | ALDH1A1 (0.46) | CYP1A2ALDH1A1THRBHPGDHSD17B10 | |
| SCHEMBL30672506 | 0.84 | ALDH1A1 (0.46) | CYP1A2ALDH1A1THRBHPGDHSD17B10 | |
| SCHEMBL580182 | 0.83 | KDM4E (0.37) | ALDH1A1HPGD | |
| SCHEMBL9613943 | 0.82 | TRPV4 (0.31) | TRPV4CYP1A2ERBB2FYNMAOA | |
| SCHEMBL5053716 | 0.82 | TRPV4 (0.31) | TRPV4CYP1A2ERBB2FYNMAOA | |
| SCHEMBL579933 | 0.76 | CA1 (0.34) | TRPV4CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL667035 | 0.76 | MPL (0.33) | TRPV4ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340076-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | The Regents of the University of California (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002046752-A9 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | UNIV CALIFORNIA (US) | 2002-08-29 | — | — | WO | disclosed |
| WO-2002046752-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-06-13 | — | — | WO | disclosed |