Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.31 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29863001 | 0.85 | CA1 (0.34) | AURKAAURKBCA12CA1CA2 | |
| SCHEMBL579933 | 0.85 | CA1 (0.34) | AURKAAURKBCA12CA1CA2 | |
| SCHEMBL7104929 | 0.85 | TRPV4 (0.34) | ALDH1A1HSD17B10CYP1A2THRBHPGD | |
| SCHEMBL11038732 | 0.81 | TRPV4 (0.36) | ALDH1A1HSD17B10 | |
| SCHEMBL9614361 | 0.80 | ALDH1A1 (0.42) | CA1CA2CA9HPRT1ALDH1A1 | |
| SCHEMBL580182 | 0.77 | KDM4E (0.37) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL5365218 | 0.76 | ALDH1A1 (0.43) | AURKAAURKBCA1CA2CA9 | |
| SCHEMBL6280639 | 0.75 | AURKA (0.56) | AURKAAURKBSUMO2SUMO1SENP7 | |
| SCHEMBL17121328 | 0.75 | AURKA (0.56) | AURKAAURKBSUMO2SUMO1SENP7 | |
| SCHEMBL866016 | 0.74 | KEAP1 (0.42) | HPRT1ALDH1A1HSD17B10CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417102-B1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LTD (GB) | 2016-04-06 | — | — | EP | claimed |
| US-9115063-B2 | Fluorophore and fluorescent sensor compound containing same | LIGHTSHIP MEDICAL LIMITED (GB) | 2015-08-25 | — | — | US | claimed |
| US-20120156793-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LIMITED (GB) | 2012-06-21 | — | — | US | claimed |
| EP-2417102-A2 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | Glysure Ltd (GB) | 2012-02-15 | — | — | EP | claimed |
| WO-2010116142-A2 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | GLYSURE LTD (GB) | 2010-10-14 | — | — | WO | claimed |
| EP-3053914-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LIMITED (GB) | 2016-08-10 | — | — | EP | disclosed |
| EP-2417102-B1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LTD (GB) | 2016-04-06 | — | — | EP | disclosed |
| US-20160033521-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LIMITED (GB) | 2016-02-04 | — | — | US | disclosed |
| US-9115063-B2 | Fluorophore and fluorescent sensor compound containing same | LIGHTSHIP MEDICAL LIMITED (GB) | 2015-08-25 | — | — | US | disclosed |
| US-20120156793-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LIMITED (GB) | 2012-06-21 | — | — | US | disclosed |
| EP-2417102-A2 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | Glysure Ltd (GB) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010116142-A2 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | GLYSURE LTD (GB) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160033521-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | QRFPR, TRPA1, GPR52 | AURKA 1554/4885AURKB 2092/4885CA12 985/4885 |
| US-20120156793-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | QRFPR, TRPA1, GPR52 | AURKA 1595/4885AURKB 2184/4885CA12 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.