Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587142 | 0.88 | POLB (0.33) | MEN1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL7104929 | 0.83 | TRPV4 (0.34) | ALDH1A1HPGD | |
| SCHEMBL11038732 | 0.78 | TRPV4 (0.36) | ALDH1A1 | |
| SCHEMBL19999168 | 0.78 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL9614361 | 0.78 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL586454 | 0.77 | AURKA (0.32) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL9930261 | 0.75 | GAA (0.36) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9929379 | 0.75 | MEN1 (0.41) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL2317725 | 0.71 | ALDH1A1 (0.59) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL31683709 | 0.71 | ALDH1A1 (0.59) | KDM4EALDH1A1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417102-B1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LTD (GB) | 2016-04-06 | — | — | EP | claimed |
| US-9115063-B2 | Fluorophore and fluorescent sensor compound containing same | LIGHTSHIP MEDICAL LIMITED (GB) | 2015-08-25 | — | — | US | claimed |
| US-20120156793-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LIMITED (GB) | 2012-06-21 | — | — | US | claimed |
| EP-2417102-A2 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | Glysure Ltd (GB) | 2012-02-15 | — | — | EP | claimed |
| WO-2010116142-A2 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | GLYSURE LTD (GB) | 2010-10-14 | — | — | WO | claimed |
| EP-3053914-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LIMITED (GB) | 2016-08-10 | — | — | EP | disclosed |
| EP-2417102-B1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LTD (GB) | 2016-04-06 | — | — | EP | disclosed |
| US-20160033521-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LIMITED (GB) | 2016-02-04 | — | — | US | disclosed |
| US-9115063-B2 | Fluorophore and fluorescent sensor compound containing same | LIGHTSHIP MEDICAL LIMITED (GB) | 2015-08-25 | — | — | US | disclosed |
| US-20120156793-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LIMITED (GB) | 2012-06-21 | — | — | US | disclosed |
| EP-2417102-A2 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | Glysure Ltd (GB) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010116142-A2 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | GLYSURE LTD (GB) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160033521-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | QRFPR, TRPA1, GPR52 | KDM4E 3336/4885ALDH1A1 483/4885MAPT 2940/4885 |
| US-20120156793-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | QRFPR, TRPA1, GPR52 | KDM4E 3256/4885ALDH1A1 477/4885MAPT 2903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.