Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392100 | 0.81 | KIF11 (0.36) | KIF11ALDH1A1TSHR | |
| SCHEMBL2394087 | 0.81 | FABP4 (0.38) | KIF11ALDH1A1TSHRHSD11B1ACHE | |
| SCHEMBL10768905 | 0.80 | KIF11 (0.35) | KIF11ALDH1A1TSHRHSD11B1ACHE | |
| SCHEMBL1369135 | 0.77 | KIF11 (0.39) | KIF11ALDH1A1TSHRHSD11B1ACHE | |
| SCHEMBL2050625 | 0.74 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL8691275 | 0.74 | AR (0.35) | KIF11ALDH1A1HSD11B1S1PR1ACHE | |
| SCHEMBL6672493 | 0.70 | FABP4 (0.38) | KIF11ALDH1A1TSHRHSD11B1ACHE | |
| SCHEMBL1445741 | 0.70 | — | — | |
| SCHEMBL456308 | 0.70 | — | — | |
| SCHEMBL526140 | 0.69 | FABP4 (0.37) | KIF11ALDH1A1TSHRHSD11B1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347990-A2 | PEPTIDE MIT INHIBIERENDER AKTIVITÄT ZUR PRODUKTION VON STICKSTOFFMONOXID | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002055541-A2 | PEPTIDES HAVING INHIBITING ACTIVITY ON THE PRODUCTION OF NITRIC OXIDE | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-07-18 | — | — | WO | disclosed |